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10 Things to Consider When Buying an In-Situ Sterilizable Bioreactor

The move from bench-scale bioreactors to larger units is a major step.making a buying decision. 1. Does What working volume do you need for each batch and, having decided this, where can a unit of the right size be installed? Cooling water A low drain with heat-resistant pipework, that must also meet local municipal standards Electrical supply (both single and three phases are often needed) Oil-free, dry air and other gasses as needed (piped or bottled) Clean, dry steam (a steam generator Process water (for Don?t forget to check that room has been allocated for peripheral equipment e.g. pumps, ...

01.09.2020

VITROCELL® Cloud Alpha 96

The VITROCELLnality enables fully automated processes with an all-in-one control unit. Everyday experiments at the air/liquid interface have never been easier. The new Cloud Alpha 96 series was developed as a result of numerous customer requests and is now capable to expose mammalian cell cultures in Corning Exposure at the Air / Liquid Interface In response to the scientific need to expose in physiologically relevant conditions, the VITROCELLances with the culture media. Cell systems cultivated on membrane inserts are exposed at the Air/Liquid Interface (ALI) so that the test substances are ...

24.08.2020

The Different Levels of Bioprocess Software: How They Address Specific User Requirements and Finding the Right One for You

Providing a single software solution to suit the full range and diversity of all biological cultivations would be an impossible task. A universal solution would be over-specified and expensive for most users, whilst similarly, a basic solution may not provide enough capabilities to suit all needs. This overview explores different user requirements and their best choice of bioprocess software. 1. Levels of a Bioprocess Software By its nature, bioprocess software is multi-layered. Different categories of users have layers in terms of the features they need from bioprocess software: Those users w ...

03.08.2020

NEW?TentaSpeed L. mono?: Testing for Listeria spp. and Listeria monocytogenes in food in 6h!

With the new rapid method "TentaSpeed L. mono", developed at the BAV INSTITUTE, low bacterial counts of The process has been successfully tested for various food groups, such as meat and fish products, dairy products and cheese, salads,< 20 CFU/g. The detection of the bacteria in the new 6-hour rapid method "TentaSpeed L. mono" is based on RT-PCR as in the 24-hour method. However, in this rapid method several steps are carried out to concentrate the bacteria before detection. The BAV INSTITUTE has thus achieved a breakthrough, as for the first time results of Do you have ...

27.07.2020

Tentamus Watcher: Detecting&Monitoring Coronavirus in Wastewater

At Tentamus Group, we are happy to announce the launch of a new web tool capable of combining the results of the analysis of the coronavirus (SARS-CoV-2) in wastewater together with indicators of health evolution: TENTAMUS WATCHER. The software generates graphics and visual information about the evolution of the coronavirus in cities and municipalities. It also provides alerts of possible outbreaks. Therefore, the tool allows public authorities to anticipate and improve the decision making. The detection of mild or asymptomatic cases through wastewater testing has become a fundamental epidemio ...

22.07.2020

NEW! Peristaltic micropumps

Innovative Sensor Technology IST AG?s latest development is the peristaltic pump series CPP1. Designed for liquids and gases, the pumps provide small flow rates in combination with reliable flow rate control and biocompatibility. The CPP1 peristaltic micropumps enable the bidirectional pumping of small amounts of liquids and gases in a controlled stream. The possible flow rates range from 150 With peristaltic pumps only the tubing is in contact with the medium, preventing contamination of the pumped liquids or gases. The media passes the pump through a medical-grade silicone tube. The CPP1 pum ...

20.07.2020

Save Time Using Automated Analysis of Chemotaxis Assays

In cooperation with MetaVi Labs, ibidi is launching FastTrack AI, an automated software solution that tracks and analyses chemotaxis data. Thanks to artificial intelligence, FastTrack AI helps you save time on your chemotaxis assays?there is no need for both manual tracking and fluorescence labeling. After sample preparation and live cell imaging (e.g., using brightfield or phase contrast microscopy), scientists can simply upload their raw image data to the cloud and will get objective and reproducible results within minutes. When using FastTrack AI, even image stacks with optically bad qualit ...

16.07.2020

Continuous Culture for Beginners

Continuous culture is best explained by discussing the basic components of the process. The theory is well known and simple to understand: Medium is both added and removed throughout much of the fermentation in order to keep cell numbers in balance. Actual execution can be difficult for starters, as there are more pumps, tubes and considerations than a simple batch fermentation. This post will look at: continuous bioprocessing modes cell retention methods how to use the antifoam pump for harvesting configuring feed and harvest pumps making aseptic connections 1. Continuous bioprocessing modes ...

01.07.2020

Mandatory maximum residue levels for chlorate and perchlorate

On 04.06.2020, the European Commission published Regulation (EU) 2020/749 amending Annex III of Regulation (EC) No. 396/2005. According to this regulation, new maximum residue levels for chlorate in food will apply starting from 28.06.2020 without transitional regulation. Chlorate is the salt of chloric acid. It is released as a by-product when disinfectants are used and when drinking water is treated, causing residues of chlorate to appear in food. Repeated ingestion of chlorate can lead to inhibited iodine absorption in humans, which can have health effects, especially for risk groups such a ...

30.06.2020

Eleva?s drug candidate to be examined for use in Covid-19 treatment

Eleva, a manufacturer of superior biologics, is exploring the potential of one of its drug candidates for first-in-line therapy of Covid-19. The compound, factor H, is part of the complement system, which is believed to affect the severity of the course of Covid-19. Eleva has developed factor H previously for a different indication and taken it through pre-clinical stages. The complement system is a vital pathway acting within the immune system. It recognizes and destroys foreign invaders and protects the body?s own cells with a special component, factor H. Insufficient amounts of factor H lea ...

25.06.2020

New GMO accreditations for Laemmegroup

Laemmegroup is proud to announce the completion of the accreditation process related to the detection of all authorized GMO in food and feed for soy, corn, rapeseed, sugar beet and in animal feed for cotton, that are listed in the latest updated European Register dated 02/08/2019. The entire accreditation process complies with Accredia Technical Regulation RT-11 art 10.1 and with UNI EN ISO/IEC 17025. The Laemmegroup Molecular Biology Laboratory is able to carry out analyses in Real Time PCR to verify that raw materials and end products for human and animal comply with the regulations applicab ...

24.06.2020

Biognosys Announces Appointment of Dr. Patrick Vink as Chairman

Biognosys, a leader in next-generation proteomics solutions for drug discovery and development, announces today the Dr. Vink has an M.D. from the University of Leiden and an MBA from the University of Rochester. He brings well as global alliance management. Prior to Cubist, he was Head of the Global Hospital Business and executive team member at Mylan Inc., Head of Global Biopharmaceuticals at Sandoz (a division of Novartis), and held various senior positions at Biogen Inc, Sanofi-Synthelabo, and Numico. Dr. Vink is currently on the board of several U.S. and European publicly listed and privat ...

17.06.2020

Safe Coronavirus research with Systec Autoclaves

The coronavirus COVID-19, which first appeared in the Chinese province of Wuhan at the turn of the year 2019/2020, has spread to all continents of the world within just a few weeks. National and international authorities are currently managing efforts to contain the virus that involve deliberately interrupting infection chains. At the same time, the virus is being examined at laboratories worldwide and bred for research purposes in order to understand how it works. This enables the development of drugs and vaccines against COVID-19 (2019-nCoV / SARS-CoV-2) in the long term. Systec autoclaves a ...

05.06.2020

Dicamba volatility tests via Humidome set-up at Symbiotic Research

SYMBIOTIC RESEARCH, LLC(SRL), announces the expansion of its agrochemical research services into conducting humidome studies with Dicamba formulations. US-EPA has requested companies marketing Dicamba formulations to use humidome set-ups to evaluate the effects of defined parameters on secondary movement of Dicamba.n of Dicamba resistant crops, agrochemical companies have started to formulate Dicamba into their formulation to prevent further weed resistance build-up. Since Dicamba is inherently volatile, it has introduced new challenges for the farmers dealing with potential damages to adjacen ...

05.06.2020

Tips for Successful Bioprocessing #1: How to Prevent Contamination

What is one of the worst things that could go wrong in your laboratory? Ask anyone working to a deadline in a bioprocess laboratory and a likely answer would be contamination of their cultures. Contamination can be hard to trace back to a source and difficult to remove if it is present in your working environment. Fortunately, there are a few simple steps you can follow to minimise the chances of this happening to you. Avoid contamination of the starter culture The most frequent cause is contamination of the starter culture. This can happen in many ways: improper handling, poor cleaning or ins ...

01.06.2020

UV-C LEDs for disinfection and sterilisation

IMM Photonics now offers powerful UV-C LEDs manufactured by the South Korean producer and IMM Photonics partner Seoul Viosys. For the wavelength 275 nm the product range includes the 1chip or 4chip SMT devices CUD8AF1D and CUD8AF4D with 19 mW and 60 mW high power output respectively. The view angle for both LED types is 120 degrees. The aluminium metal body ensures high thermal conductivity. The small size and low energy consumption of the UV-C LEDs allows for quick and easy integration into existing design concepts. The main applications of UV-C LEDs are the disinfection and sterilisation of ...

07.05.2020

Good Bioreactor Design: How It Creates An Outstanding User Experience

Stefan Sperling is an industrial designer at the Meyer-Hayoz Design Engineering Group in Switzerland. He is part of the specialist team who was responsible for designing the award-winning INFORS HTMinifors 2MultitronMinitron. In this interview, Mr. Sperling shares his view on what constitutes good product design. Mr. Sperling, what exactly is industrial design? Industrial design is an important part of product development?one that harmonizes all of the factors that affect the product. Functional shaping, usability, materials and production technology are all examples of very important issues s ...

04.05.2020

Gustave Roussy and Biognosys Announce Partnership

The severe pneumonitis in patients infected by the severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) requires prolonged treatment in intensive care units with mechanical ventilation. This has led to overwhelmed hospital facilities and the shortage of medical supplies in countries profoundly affected by the COVID-19 pandemic. Recent data from hospitals in China, Italy, and France have shown that severe pneumonitis is associated with cytokine storm induced by high serum levels of cytokines and chemokines. The pro-inflammatory cytokine Interleukin-6 (IL-6) is known to have a prominent ...

28.04.2020

Nanion Technologies and NEXEL partner to open a new reference demonstration laboratory in South Korea

April 17th 2020: Nanion Technologies GmbH, a leading provider of automated patch clamp and cell monitoring systems, announces the partnership with NEXEL Co., Ltd., specialists in the manufacturing of hiPSC-derived cells. Under the partnership NEXEL will provide demonstration infrastructure in South Korea for Nanion Nanion Technologies and NEXEL are pleased to announce a partnership, focused on combining Nanion?s CardioExcyte 96 and FLEXcyte 96 cell monitoring technology with NEXEL?s hiPSC-derived cells for demonstration purposes. Bringing together the two companies? infrastructure and expertis ...

17.04.2020

Typical Cultivation Parameters for Cell Cultures

Getting started with cell culture can seem like an overwhelming step: cells are sensitive to shear stress, have a high risk of contamination and are very demanding concerning the right choice of process parameters. Check our blog post for all you need to start shaking or running your bioreactor with mammalian cells, insect cells and plant cells. 1. Mammalian cells Proteins obtained from mammalian cells play an important role in the biotech industry for manufacturing therapeutic medicines. The best known mammalian cells are HEK (human embryonic kidney) cells, which are relatively easy to handle ...

08.04.2020


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