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Continuous Culture for Beginners

Continuous culture is best explained by discussing the basic components of the process. The theory is well known and simple to understand: Medium is both added and removed throughout much of the fermentation in order to keep cell numbers in balance. Actual execution can be difficult for starters, as there are more pumps, tubes and considerations than a simple batch fermentation. This post will look at: continuous bioprocessing modes cell retention methods how to use the antifoam pump for harvesting configuring feed and harvest pumps making aseptic connections 1. Continuous bioprocessing modes ...

01.07.2020

Mandatory maximum residue levels for chlorate and perchlorate

On 04.06.2020, the European Commission published Regulation (EU) 2020/749 amending Annex III of Regulation (EC) No. 396/2005. According to this regulation, new maximum residue levels for chlorate in food will apply starting from 28.06.2020 without transitional regulation. Chlorate is the salt of chloric acid. It is released as a by-product when disinfectants are used and when drinking water is treated, causing residues of chlorate to appear in food. Repeated ingestion of chlorate can lead to inhibited iodine absorption in humans, which can have health effects, especially for risk groups such a ...

30.06.2020

Eleva?s drug candidate to be examined for use in Covid-19 treatment

Eleva, a manufacturer of superior biologics, is exploring the potential of one of its drug candidates for first-in-line therapy of Covid-19. The compound, factor H, is part of the complement system, which is believed to affect the severity of the course of Covid-19. Eleva has developed factor H previously for a different indication and taken it through pre-clinical stages. The complement system is a vital pathway acting within the immune system. It recognizes and destroys foreign invaders and protects the body?s own cells with a special component, factor H. Insufficient amounts of factor H lea ...

25.06.2020

New GMO accreditations for Laemmegroup

Laemmegroup is proud to announce the completion of the accreditation process related to the detection of all authorized GMO in food and feed for soy, corn, rapeseed, sugar beet and in animal feed for cotton, that are listed in the latest updated European Register dated 02/08/2019. The entire accreditation process complies with Accredia Technical Regulation RT-11 art 10.1 and with UNI EN ISO/IEC 17025. The Laemmegroup Molecular Biology Laboratory is able to carry out analyses in Real Time PCR to verify that raw materials and end products for human and animal comply with the regulations applicab ...

24.06.2020

Biognosys Announces Appointment of Dr. Patrick Vink as Chairman

Biognosys, a leader in next-generation proteomics solutions for drug discovery and development, announces today the Dr. Vink has an M.D. from the University of Leiden and an MBA from the University of Rochester. He brings well as global alliance management. Prior to Cubist, he was Head of the Global Hospital Business and executive team member at Mylan Inc., Head of Global Biopharmaceuticals at Sandoz (a division of Novartis), and held various senior positions at Biogen Inc, Sanofi-Synthelabo, and Numico. Dr. Vink is currently on the board of several U.S. and European publicly listed and privat ...

17.06.2020

Safe Coronavirus research with Systec Autoclaves

The coronavirus COVID-19, which first appeared in the Chinese province of Wuhan at the turn of the year 2019/2020, has spread to all continents of the world within just a few weeks. National and international authorities are currently managing efforts to contain the virus that involve deliberately interrupting infection chains. At the same time, the virus is being examined at laboratories worldwide and bred for research purposes in order to understand how it works. This enables the development of drugs and vaccines against COVID-19 (2019-nCoV / SARS-CoV-2) in the long term. Systec autoclaves a ...

05.06.2020

Dicamba volatility tests via Humidome set-up at Symbiotic Research

SYMBIOTIC RESEARCH, LLC(SRL), announces the expansion of its agrochemical research services into conducting humidome studies with Dicamba formulations. US-EPA has requested companies marketing Dicamba formulations to use humidome set-ups to evaluate the effects of defined parameters on secondary movement of Dicamba.n of Dicamba resistant crops, agrochemical companies have started to formulate Dicamba into their formulation to prevent further weed resistance build-up. Since Dicamba is inherently volatile, it has introduced new challenges for the farmers dealing with potential damages to adjacen ...

05.06.2020

Tips for Successful Bioprocessing #1: How to Prevent Contamination

What is one of the worst things that could go wrong in your laboratory? Ask anyone working to a deadline in a bioprocess laboratory and a likely answer would be contamination of their cultures. Contamination can be hard to trace back to a source and difficult to remove if it is present in your working environment. Fortunately, there are a few simple steps you can follow to minimise the chances of this happening to you. Avoid contamination of the starter culture The most frequent cause is contamination of the starter culture. This can happen in many ways: improper handling, poor cleaning or ins ...

01.06.2020

UV-C LEDs for disinfection and sterilisation

IMM Photonics now offers powerful UV-C LEDs manufactured by the South Korean producer and IMM Photonics partner Seoul Viosys. For the wavelength 275 nm the product range includes the 1chip or 4chip SMT devices CUD8AF1D and CUD8AF4D with 19 mW and 60 mW high power output respectively. The view angle for both LED types is 120 degrees. The aluminium metal body ensures high thermal conductivity. The small size and low energy consumption of the UV-C LEDs allows for quick and easy integration into existing design concepts. The main applications of UV-C LEDs are the disinfection and sterilisation of ...

07.05.2020

Good Bioreactor Design: How It Creates An Outstanding User Experience

Stefan Sperling is an industrial designer at the Meyer-Hayoz Design Engineering Group in Switzerland. He is part of the specialist team who was responsible for designing the award-winning INFORS HTMinifors 2MultitronMinitron. In this interview, Mr. Sperling shares his view on what constitutes good product design. Mr. Sperling, what exactly is industrial design? Industrial design is an important part of product development?one that harmonizes all of the factors that affect the product. Functional shaping, usability, materials and production technology are all examples of very important issues s ...

04.05.2020

Gustave Roussy and Biognosys Announce Partnership

The severe pneumonitis in patients infected by the severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) requires prolonged treatment in intensive care units with mechanical ventilation. This has led to overwhelmed hospital facilities and the shortage of medical supplies in countries profoundly affected by the COVID-19 pandemic. Recent data from hospitals in China, Italy, and France have shown that severe pneumonitis is associated with cytokine storm induced by high serum levels of cytokines and chemokines. The pro-inflammatory cytokine Interleukin-6 (IL-6) is known to have a prominent ...

28.04.2020

Nanion Technologies and NEXEL partner to open a new reference demonstration laboratory in South Korea

April 17th 2020: Nanion Technologies GmbH, a leading provider of automated patch clamp and cell monitoring systems, announces the partnership with NEXEL Co., Ltd., specialists in the manufacturing of hiPSC-derived cells. Under the partnership NEXEL will provide demonstration infrastructure in South Korea for Nanion Nanion Technologies and NEXEL are pleased to announce a partnership, focused on combining Nanion?s CardioExcyte 96 and FLEXcyte 96 cell monitoring technology with NEXEL?s hiPSC-derived cells for demonstration purposes. Bringing together the two companies? infrastructure and expertis ...

17.04.2020

Typical Cultivation Parameters for Cell Cultures

Getting started with cell culture can seem like an overwhelming step: cells are sensitive to shear stress, have a high risk of contamination and are very demanding concerning the right choice of process parameters. Check our blog post for all you need to start shaking or running your bioreactor with mammalian cells, insect cells and plant cells. 1. Mammalian cells Proteins obtained from mammalian cells play an important role in the biotech industry for manufacturing therapeutic medicines. The best known mammalian cells are HEK (human embryonic kidney) cells, which are relatively easy to handle ...

08.04.2020

Complete-off and crosstalk-free Multi Laser Engine: Four-color Laser Combiner for Biophotonics&Microscopy

Customers can take care of their research without the need to ever manually align their illumination source. Hands free operation and auto-alignment makes it a perfect fit for OEM customers. TOPTICA''s iChrome CLE is a compact laser engine that combines four laser lines in one box. All integrated colors are provided via one polarization-maintaining single-mode fiber. It is available with 405, 488, 561 and 640 nm and more than 50 mW guaranteed output power after the fiber each. Easy OEM integration is enabled via the fully unified user interface. With its auto-alignment feature the la ...

03.03.2020

Swimming Against the Tide: How The Ocean Cleanup uses DURAN® glassware in their Microplastic Pollution Research

The pollution of the oceans by plastic is one of the biggest problems of our time. Every year, an estimated 200 million tons of garbage end up in the sea, 6.4 million tons of which is plastic. The Ocean Cleanup In a research laboratory, marine samples are examined for the presence and types of microplastic contamination. The research helps to understand the dynamics of microplastic pollution formation and dispersal in the oceans. The researchers use DURAN Other institutes around the world have also chosen DURANf Putra Malaysia and the Alzahra University in Iran. DURANwith other substances. The ...

27.02.2020

Swimming Against the Tide: How The Ocean Cleanup uses DURAN® glassware in their Microplastic Pollution Research

The pollution of the oceans by plastic is one of the biggest problems of our time. Every year, an estimated 200 million tons of garbage end up in the sea, 6.4 million tons of which is plastic. The Ocean Cleanup In a research laboratory, marine samples are examined for the presence and types of microplastic contamination. The research helps to understand the dynamics of microplastic pollution formation and dispersal in the oceans. The researchers use DURAN Other institutes around the world have also chosen DURANf Putra Malaysia and the Alzahra University in Iran. DURANwith other substances. The ...

27.02.2020

Swimming Against the Tide: How The Ocean Cleanup uses DURAN® glassware in their Microplastic Pollution Research

The pollution of the oceans by plastic is one of the biggest problems of our time. Every year, an estimated 200 million tons of garbage end up in the sea, 6.4 million tons of which is plastic. The Ocean Cleanup In a research laboratory, marine samples are examined for the presence and types of microplastic contamination. The research helps to understand the dynamics of microplastic pollution formation and dispersal in the oceans. The researchers use DURAN Other institutes around the world have also chosen DURANf Putra Malaysia and the Alzahra University in Iran. DURANwith other substances. The ...

27.02.2020

Swimming Against the Tide: How The Ocean Cleanup uses DURAN® glassware in their Microplastic Pollution Research

The pollution of the oceans by plastic is one of the biggest problems of our time. Every year, an estimated 200 million tons of garbage end up in the sea, 6.4 million tons of which is plastic. The Ocean Cleanup In a research laboratory, marine samples are examined for the presence and types of microplastic contamination. The research helps to understand the dynamics of microplastic pollution formation and dispersal in the oceans. The researchers use DURAN Other institutes around the world have also chosen DURANf Putra Malaysia and the Alzahra University in Iran. DURANwith other substances. The ...

27.02.2020

Femtosecond Fiber Laser Optimized for 2-Photon Microscopy

2-photon fluorescence microscopy has become a key technology in biological imaging enabling three-dimensional, noninvasive studies of biological tissue on the submicron scale. TOPTICA proudly presents the FemtoFiber ultra 920, a cost-effective, turn-key and flexible light source that is fully tailored to the excitation of GFP or other fluorophores and provides maximum image brightness. With more than sufficient output power, shortest pulses, and our unique Clean-Pulse Technology, the FemtoFiber ultra 920 features the highest relative peak power and enables unmatched brightness in 2-photon micr ...

19.02.2020

MyBiotech GmbH: One location - one company - bundled knowledge and experience!

The two life science companies MyBiotech GmbH and MJR PharmJet GmbH are combined in a merger of equals and will continue their business under the trademark of MyBiotech. In January 2020, MyBiotech GmbH, a start-up company in the biotech industry, and MJR The merger will not remain the only major change in utical sector will take place under strict regulations according to GMP. The combination of biotechnology and pharmaceutical development is unique in this form, and will help MyBiotech to further grow and expand.", said Dr. Emre T Both companies are partners of the Instillo ...

12.02.2020


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